“Clever Little Lies,” a 2013 comedy by the Tony Award-winning playwright Joe DiPietro that premiered last fall at the George Street Playhouse in New Brunswick, N.J., will open at Guild Hall on Wednesday and run through Aug. 3. The original cast — Marlo Thomas, Greg Mullavey, Jim Stanek, and Kate Wetherhead — will appear in the production, which will be directed by David Saint, artistic director of George Street Playhouse.